CAFFEINE AS A TOOL FOR INVESTIGATING THE INTEGRATION OF CDC25 PHOSPHORYLATION, ACTIVITY AND UBIQUITIN-DEPENDENT DEGRADATION IN SCHIZOSACCHAROMYCES POMBE

Abstract The evolutionarily conserved Cdc25 phosphatase is an essential protein that removes inhibitory phosphorylation moieties on the mitotic regulator Cdc2.Together with the Wee1 kinase, a negative regulator of Cdc2 activity, Cdc25 is thus a central regulator of cell cycle progression in Schizosaccharomyces pombe.The expression and Audio Recieve

Excess export of nitrate to streams affects ecosystem structure and functions and has been an environmental issue attracting worldwide attention.The dynamics of catchment-scale solute export from diffuse nitrogen sources can be explained by the changes of dominant Sleep flow paths, as solute attenuation (including the degradation of nitrate) is lin

The bleeding of cementitious materials corresponds to the settlement of the granular skeleton accompanied by the accumulation of water at the surface (bleed water).Part of this water (internal bleeding) remains trapped under the aggregates (sand or gravel) or the reinforcements.The excess of this trapped water can weaken the bond between the cement